IL-5 Protéine
Aperçu rapide pour IL-5 Protéine (ABIN935494)
Antigène
Voir toutes IL-5 (IL5) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES
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Attributs du produit
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Purified recombinant Human IL5 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ? 0.15 ng/mL, corresponding to a specific activity of ? 6.6 x 10^6 units/mg. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with distilled water to a concentration of 0.1 - 1.0 mg/mL.
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Buffer
- Lyophilized from 20 mM Na3PO4, pH 7.5.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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- IL-5 (IL5) (Interleukin 5 (IL5))
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Autre désignation
- IL5
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Sujet
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IL5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and Mouse IL5 is cross-species reactive.
Alternative Names: IL 5 protein, Interleukin 5 protein, IL5, EDF protein, IL 5, IL-5, IL-5 protein, BCDFII protein, TRF protein, IL-5 protein -
Poids moléculaire
- 26 kDa
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Pathways
- Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
Antigène
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